Health
Making a difference in healthcare
Our world-leading researchers focus on the development and treatment of new avenues for the prevention, diagnosis and treatment of major public health problems that affect millions of people globally.
These medical problems include eye disease, diabetic complications, cardiovascular disease, antibiotic resistance and common lung illnesses such as asthma, COPD, cystic fibrosis and pneumonia.
Our inter-disciplinary research delivers innovative and translational science research, alongside insightful health services discoveries, leading to real-world impact in health and healthcare, beyond the lab.
Vision and Vascular Medicine
The Wellcome-Wolfson Institute for Experimental Medicine is internationally recognized for its research in Ophthalmology and Diabetic Vascular Disease.
The Vision and Vascular Medicine Theme includes 16 teams focusing on clinical trials, diagnostics, pathology, and drug discovery. Key research areas in Ophthalmology target diabetic retinopathy and age-related macular degeneration (AMD), exploring early molecular events that lead to these conditions. Clinical trials, including the DIAMONDS Trial, are investigating treatments for diabetic macular oedema (DMO). Additionally, the Diabetes and Vascular Research focuses on diabetic cardiomyopathy, peripheral vascular disease, and nephropathy, with several groups studying stem cells for microvascular regeneration.
Respiratory Medicine
Our Respiratory Medicine research groups focus on translational research for asthma, COPD, cystic fibrosis, and acute respiratory distress syndrome, involving pre-clinical development and Phase I-III clinical trials. These trials are a mix of investigator-led and industry collaborations. Research also aims to establish quality criteria and outcome measures for clinical trials. Fundamental research complements this by exploring the molecular and cellular mechanisms of these diseases. Key discoveries include the dysregulation of the immune response in lung inflammation, the role of the lung microbiome in cystic fibrosis, and asthma biomarkers. This work informs pre-clinical studies on therapies like anti-protease inhibitors and stem cells to treat lung conditions.
Antimicrobial Resistant Infections
Research in this area focuses on enhancing the prevention, detection, and treatment of infections.
Efforts are centered on preventing antimicrobial resistance through better antimicrobial stewardship, improving infection detection using molecular and sensor technologies, and preventing infections with innovative anti-infective biomaterials. Additionally, the research aims to improve infection control strategies and develop new antibiotics, antibiotic adjuvants, and markers to guide more effective, evidence-based antibiotic selection.
Cancer Research
Our mission in cancer research is to improve patient outcomes, train the next generation of scientists/clinicians and enhance the competitiveness of the UK life sciences sector.
The Patrick G Johnston Centre for Cancer Research at Queen's University Belfast is a cross-Faculty, interdisciplinary research centre with over 300 clinical and basic researchers from across the world and is committed to the highest quality of research excellence. Our world-leading research harnesses a close, collaborative interaction between clinical and laboratory research experts that ultimately enhances the quality and scope of our integrated basic and clinical research programmes in cancer as well as other diseases.
Diabetes and Endocrinology
Our research in endocrinology explores hormonal functions and related diseases.
Work spans areas such as diabetes, thyroid disorders, and hormone-driven cancers. Researchers at Queen’s focus on understanding the molecular mechanisms behind these conditions, developing novel therapeutic approaches, and improving patient outcomes. Collaborative efforts drive advancements in endocrinology, contributing to a deeper understanding of the role hormones play in health and disease.
Cardiology
Queen’s research in cardiology focuses on understanding cardiovascular diseases, improving diagnostic techniques, and developing new treatments.
The research covers heart failure, hypertension, and vascular complications, with significant work on understanding the molecular and genetic mechanisms driving these conditions. Our research aims to enhance clinical outcomes through personalized medicine, pioneering therapeutic strategies, and advancing preventative measures for heart disease. These efforts contribute to major advancements in cardiovascular healthcare and patient quality of life.
Nanomedicine and Biotherapeutics
Research in this theme focuses on developing innovative technologies and targeted therapies for healthcare.
Key activities include creating genetic therapies and delivery systems for cancer detection and treatment, designing strategies to detect and inhibit proteases involved in chronic diseases, isolating bioactive peptides for therapeutic use, and utilizing computational biology for drug design and molecular modeling. These advancements aim to address complex health challenges and improve therapeutic outcomes.
Healthcare Technologies and Biomedical Engineering
Queen's research in bioengineering has been at the forefront of innovation, improving patient quality of life through novel healthcare technologies. The interdisciplinary approach adopted by Queen's researchers has led to groundbreaking developments in the design and application of biomaterials with multiple functions, catering to the diverse needs of medical interventions. The exploration of bioresorbable materials has opened new avenues in implant technology, providing solutions that are both effective and environmentally conscious.
Additionally, Queen's has been instrumental in the integration of 3D printing technologies in bioengineering, revolutionizing the manufacturing of custom implants and prosthetics. This comprehensive research portfolio not only contributes significantly to the field of bioengineering but also translates into tangible advancements in patient care and medical technology.
Nursing and Midwifery
Within the School of Nursing and Midwifery our area of strength is health innovation through co-design and rigorous evaluation of health promoting and healthcare interventions with policymakers, practice partners, patients and carers. Research themes encapsulate lifespan health research from conception to end-of-life. The Maternal and Child Health theme adopts a multidisciplinary approach to high-risk groups during pregnancy, childbirth, infancy, and childhood, focusing on maternity care and child health from population-level studies to individual care needs. The Chronic Illness and Palliative Care theme explores the experiences of cancer survivors, palliative care patients, and their carers, aiming to enhance survivorship and end-of-life care.
Chronic Illness and Palliative Care
The Chronic Illness and Palliative Care research theme involves patients, families, and clinicians in innovative research aimed at enhancing the health and well-being of individuals with chronic illnesses and those receiving palliative care. The interdisciplinary team addresses significant challenges, utilizing Artificial Intelligence for personalized patient support in heart failure and improving advance care planning for dementia and end-stage kidney disease. They prioritize co-design, integrating patient and family input into developing effective solutions, such as social prescribing, online platforms for cancer support, and exercise prescriptions for chronic illness management.
Surgical Medicine
Queen's researchers contribute to new therapies and diagnostic tools, with a focus on minimally invasive surgical techniques across fields like dentistry and ophthalmology, aiming to perfect procedures causing minimal tissue disruption. Queen's is addressing the global shortage of qualified surgeons through innovations in medical robotics, presenting groundbreaking contributions to the field including robotic assisted eye surgery. The Patrick G. Johnston Centre for Cancer Research trains the next generation of scientists and clinicians, equipping them with the knowledge and skills to tackle the complexities of cancer. The centre fosters innovation and collaboration to strengthen the UK life sciences sector and improve cancer treatment and patient outcomes.
Public Health Nutrition
The Public Health Nutrition Group focuses on advancing nutrition research and promoting public health across all age groups. Collaborating with the Centre for Public Health, the School of Biological Sciences, and the Institute for Global Food Security, they also maintain a wide network of national and international partners, including Harvard TH Chan School of Public Health and the University of California San Francisco. Current projects include research on school food, food-based biomarkers, diet quality, cardiovascular health, neurocognitive aging in diabetes, and weight management during pregnancy. The group has a strong record of supervising postgraduate students and provides a vibrant, supportive environment for nutrition research with regular meetings.
OUR EXPERTISE
OUR RESEARCH HUBS
Our research integrates the full translational and innovation spectrum, spanning from fundamental discovery science, leveraging molecular/cellular/human models, to co-design and evaluation of health and healthcare solutions with end-users and developing innovative solutions and therapeutics to benefit industry and healthcare.
