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Plant-derived phytotheraputics against resistant bacteria

School of Biological Sciences | PHD

Applications are now CLOSED
Funding
Funded
Reference Number
SBIO-2020-1241
Application Deadline
29 February 2024
Start Date
1 October 2024

Overview

Antimicrobial resistance (AMR) has been declared by WHO as one of the top global public health threats facing humanity. Misuse and overuse of antimicrobials are the main drivers in the development of drug-resistant pathogens. This project aims to evaluate phytochemicals as safe, effective, and sustainable antibiotic alternatives to combat AMR.

Reducing unnecessary use of antibiotics to preserve effectiveness of existing antimicrobials, and utilising antibiotic alternatives are among the current global actions to combat AMR. The continual use of herbal medicines to date in many parts of the world supports the anecdotal effectiveness of phytochemicals against human and animal infections. Recent scientific evidence suggests that medicinal plants and their phytochemicals possess potent antibacterial properties again many pathogenic bacteria including their resistant strains. This project seeks to provide scientific evidence of the efficacy of plant substances (phytochemicals) against resistant bacteria and to elucidate their underlying antibacterial mechanisms using contemporary scientific tools and advanced technological platforms interlinking different disciplines of biology, microbiology, biochemistry, molecular biology and biotechnology.

Postgraduate Research applicants who are interested in applying for this fully funded studentship must have applied to Queen’s University Belfast, via the Direct Applications Portal (link below), and submitted all required supporting documents by the closing date: https://dap.qub.ac.uk/portal/user/u_login.php For further information about academic requirements please see below: https://www.qub.ac.uk/courses/postgraduate-research/biological-sciences-phd.html

Funding Information

Funded by the Department for the Economy (DfE). For UK domiciled students the value of an award includes the cost of approved tuition fees and maintenance support the 2024/25 rates are still to be confirmed (current rates for 2023/24 are Fees £4,712, Stipend £18,622). To be considered eligible you must have been ordinarily resident in the UK for the full 3-year period prior to the start of the studentship and you must be ordinarily resident in Northern Ireland on the first day of the start of the studentship. For further information about eligibility criteria please refer to the DfE Postgraduate Studentship Terms and Conditions at https://www.economy-ni.gov.uk/publications/student-finance-postgraduate-studentships-terms-and-conditions

Project Summary
Supervisor

Dr Chen Situ

Research Profile


Mode of Study

Full-time: 3 Years


Funding Body
DfE
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