MSci Medicinal Chemistry
Academic Year 2018/19
A programme specification is required for any programme on which a student may be registered. All programmes of the University are subject to the University's Quality Assurance processes. All degrees are awarded by Queen's University Belfast.
Programme Title |
MSci Medicinal Chemistry |
Final Award |
Master in Science |
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Programme Code |
MDC-MSCI |
UCAS Code |
F15A |
HECoS Code |
100420 |
ATAS Clearance Required |
No |
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Mode of Study |
Full Time |
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Type of Programme |
Undergraduate Master |
Length of Programme |
4 Academic Year(s) |
Total Credits for Programme |
480 |
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Exit Awards available |
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INSTITUTE INFORMATION
Teaching Institution |
Queen's University Belfast |
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School/Department |
Chemistry & Chemical Engineering |
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Framework for Higher Education Qualification Level |
Level 7 |
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QAA Benchmark Group |
Chemistry |
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Accreditations (PSRB) |
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Royal Society of Chemistry |
Date of most recent Accreditation Visit 14-04-16 |
REGULATION INFORMATION
Does the Programme have any approved exemptions from the University General Regulations
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Programme Specific Regulations Students with an average mark of <55% at the end of Stage 2 or a weighted average mark of <55 % across Stages 1 & 2, will be transferred to the BSc in Medicinal Chemistry programme. |
Students with protected characteristics
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Are students subject to Fitness to Practise Regulations (Please see General Regulations) No |
EDUCATIONAL AIMS OF PROGRAMME
Understand the core principles of chemistry with an emphasis on drug design and synthetic chemistry towards medicinal applications.
Progress directly from the MSci to graduate level employment in pharmaceutical industry and other chemistry and non-chemistry related industries or alternatively progress to postgraduate study or research.
Prepare for eligibility for professional recognition and the status “Chartered Chemist” through full membership of the Royal Society of Chemistry
Demonstrate professional skills within an academic setting through a dedicated medicinal chemistry research project
LEARNING OUTCOMES
Learning Outcomes: Cognitive SkillsOn the completion of this course successful students will be able to: |
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Solve previously 'unseen' scientific problems using a range of analytical and deductive techniques |
Teaching/Learning Methods and Strategies Lectures and tutorials; class tests and problem solving sessions; structured group and independent laboratory classes; guided independent study. Unseen problems are introduced with tutorial and post-laboratory questions in all topics at Stages 1 and 2 and increase in complexity into level 3 leading to the design of experiments and data acquisition to solve research questions Methods of Assessment Written examinations; project or extended experimental work dissertations; oral and poster presentations; experimental reports; |
Develop and use reflective practices to provide practical solutions to problems by experimentation |
Teaching/Learning Methods and Strategies Lectures and tutorials; structured group and independent laboratory classes; research project or extended experimental work; group problem solving exercises; guided independent study. Reflective practices are developed through feedback from experimental reports, tutorial work and formative/summative class tests. By Stage 3, students are routinely applying reflective experimental design principles to their research project or extended practical programmes Methods of Assessment Written examinations; group and individual dissertations; oral and poster presentations; experimental reports |
Critically review and reflect upon their work |
Teaching/Learning Methods and Strategies Structured group and independent laboratory classes; research project or extended experimental work; group problem solving exercises. The same principles of developing these critical analysis and review techniques as the previous Outcome apply here Methods of Assessment Written examinations; group and individual dissertations; oral and poster presentations; experimental reports |
Make value judgments on information in the public domain |
Teaching/Learning Methods and Strategies Essays; literature searching and research project or extended experimental work dissertation. Retrieval of subject-specific material from primary literature and public domain sources are developed through essays and particularly through the group problem solving exercises which rely on critical analysis of published material Methods of Assessment Group and individual dissertations; oral and poster presentations. |
Learning Outcomes: Transferable SkillsOn the completion of this course successful students will be able to: |
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Demonstrate numeracy and literacy skills |
Teaching/Learning Methods and Strategies Lectures and workshops; structured group and independent laboratory classes; research project or extended experimental work; group problem solving exercises. Students enter the degree pathway with different levels of mathematics and there is an emphasis in Stage 1 of bringing all students to a core threshold of mathematical skills through lectures and workshops. Scientific literacy is developed through increasingly challenging and rigorous experimental reports as students progress from Stage 1 to their project extended practical dissertation Methods of Assessment Written examinations; project or extended experimental work dissertations; oral and poster presentations; experimental reports; |
Work within a team based environment and employ interpersonal skills |
Teaching/Learning Methods and Strategies Research project or extended experimental work; group problem solving exercises. Team work starts in Stage 1 where students work in small groups in some of the laboratory classes and learn the importance of division of tasks and reliance on shared data. A centrepiece of the group exercise strategy is the extended group process design problem solving exercise at Stage 2 leading to the research project or extended practical module at Stage 3 which requires students to work effectively in existing post-graduate research groups Methods of Assessment Project or extended experimental work dissertations; group and individual dissertations; oral and poster presentations |
Effectively exert generic problem-solving skills |
Teaching/Learning Methods and Strategies Lectures and tutorials; class tests and problem solving sessions; group problem solving exercises; guided independent study. Problem solving skills are central to this degree programme and are incorporated to a greater or lesser extent in all activities at all Stages Methods of Assessment Written examinations; project or extended experimental work dissertations; oral and poster presentations; experimental reports |
Manage time effectively and prioritise workloads |
Teaching/Learning Methods and Strategies research project or extended experimental work; coursework deadlines, project goals, milestones and submission targets provide a framework for developing these skills Methods of Assessment Project or extended experimental work dissertations; group and individual dissertations; |
communicate effectively with colleagues and others using both written and oral methods |
Teaching/Learning Methods and Strategies Research project or extended experimental work and dissertation; group problem solving. exercises; oral and poster presentations Written and oral presentation skills are introduced at Stage 1 through regular tutorials and a poster session on a given topic and are developed further through Stages 2 and 3 with several modules requiring oral or poster presentations and written essays and dissertations. The importance of scientific rigour in the defence of arguments is developed through these exercises Methods of Assessment Project or extended experimental work dissertations; group and individual dissertations; oral and poster presentations |
Demonstrate data analysis and processing techniques |
Teaching/Learning Methods and Strategies Structured group and independent laboratory classes; research project or extended experimental work and dissertation; class tests and problem solving sessions; guided independent study. The processing of complex sets of information and data is developed from simple experimental results interpretation in Stage 1 through to unknown data processing in the research project or extended practical work in Stage 3. Methods of Assessment Project or extended experimental work dissertations; group and individual dissertations; oral and poster presentations |
Learning Outcomes: Knowledge & UnderstandingOn the completion of this course successful students will be able to: |
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Read, understand and assimilate new information and subsume acquired knowledge into a concise manner and within various settings |
Teaching/Learning Methods and Strategies Lectures and tutorials; structured group and independent laboratory classes; research project or extended experimental work; essays and dissertations. The ability to extract, process, understand and critically analyse published material is a core key skill in this degree programme and the techniques are embedded into the course from Stage 1 to 3 using the methods listed above Methods of Assessment Written examinations; class tests; project or extended experimental work dissertations; oral and poster presentations; experimental reports; |
Apply developed generic and subject specific IT skills |
Teaching/Learning Methods and Strategies Lectures and tutorial; IT and computer skills workshops; experimental reports; research project or extended experimental work; essays and dissertations; guided independent study. Basic IT skills for the production of professional reports using subject specific software, such as chemical structure drawing and data analysis, are introduced through workshops and computer-based classes and then developed through experimental reports and essays and dissertations Methods of Assessment Written examinations; class tests; project or extended experimental work dissertations; computer-based workshop or online assessment; experimental reports; |
Be proficient in database and literature searching techniques |
Teaching/Learning Methods and Strategies Essays; literature searching and research project or extended experimental work dissertation; group problem solving exercises; guided independent study. Awareness of the body of published scientific work and the tools to interrogate and access that information begins in Stage 1 and is developed to the point where students use the available search techniques routinely for their research project or extended practical work in Stage 3 Methods of Assessment Project or extended experimental work dissertations; group and individual dissertations; oral and poster presentations |
Learning Outcomes: Subject SpecificOn the completion of this course successful students will be able to: |
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Demonstrate a conceptual understanding of the fundamental aspects of organic, inorganic and physical chemistry |
Teaching/Learning Methods and Strategies Lectures and tutorials; structured group and independent laboratory classes; research project or extended experimental work; essays and dissertations; guided independent study; These subject-specific skills are developed from fundamental concepts in Stages 1 and 2 to the application of the concepts in industrially and commercially relevant contexts in Stages 3 and 4 where a degree of specialisation is available Methods of Assessment Written examinations; class tests; project or extended experimental work dissertations; experimental reports |
Understand the characteristic chemistry and properties of the elements and group relationships and trends within the periodic table |
Teaching/Learning Methods and Strategies Lectures and tutorials; structured group and independent laboratory classes; essays and dissertations; guided independent study. See previous Learning Outcome for details of strategy Methods of Assessment Written examinations; class tests; project or extended experimental work dissertations; experimental reports |
Demonstrate a knowledge of chemical bonding, shape and structure |
Teaching/Learning Methods and Strategies Lectures and tutorials; structured group and independent laboratory classes; essays and dissertations; independent guided study. See previous Learning Outcome for details of strategy Methods of Assessment Written examinations; class tests; project or extended experimental work dissertations; experimental reports |
Understand the chemistry of functional groups and major synthetic pathways in organic chemistry. |
Teaching/Learning Methods and Strategies Lectures and tutorials; structured group and independent laboratory classes; essays and dissertations; guided independent study. See previous Learning Outcome for details of strategy Methods of Assessment Written examinations; class tests; project or extended experimental work dissertations; experimental reports |
Understand the principles of thermodynamics and kinetics, including catalysis and the mechanistic interpretation of chemical reactions |
Teaching/Learning Methods and Strategies Lectures and tutorials; structured group and independent laboratory classes; essays and dissertations; guided independent study. See previous Learning Outcome for details of strategy Methods of Assessment Written examinations; class tests; project or extended experimental work dissertations; experimental reports |
Demonstrate safe and proficient practical laboratory chemistry skills |
Teaching/Learning Methods and Strategies Structured group and independent laboratory classes; research project. Chemistry is essentially an experimental, laboratory-based subject and experimental work forms at least 25% of the degree in terms of teaching and assessment. Developing the skills to handle potentially dangerous materials and processes is central to all laboratory-based activities Methods of Assessment Project or extended experimental work dissertations; group and individual dissertations; oral and poster presentations; experimental reports |
Be proficient in a range of analytical instrumentation |
Teaching/Learning Methods and Strategies Structured group and independent laboratory classes; research project or extended experimental work; group problem solving exercises. Methods of Assessment Project or extended experimental work dissertations; group and individual dissertations; oral and poster presentations; experimental reports |
Demonstrate advanced knowledge of an area of new or emerging chemical research |
Teaching/Learning Methods and Strategies Students can choose up to two areas of specialisation in Stage 4 to support and complement their research project and the core medicinal chemistry material. Core material is delivered by lectures but students make extensive use of guided independent study to acquire knowledge from peer reviewed literature Methods of Assessment Written examinations; class tests; essays and dissertations; oral presentations |
Understand the general concepts used in drug design related to the pharmacodynamic and pharmacokinetic properties of putative therapeutic agents |
Teaching/Learning Methods and Strategies Lectures and workshops; guided independent study and literature review. Strategy as in previous learning outcome Methods of Assessment Written examinations; class tests; essay; experimental reports |
Understand the mechanisms of the modes of action of the major classes of drugs |
Teaching/Learning Methods and Strategies Lectures and workshops; guided independent study and literature review. Strategy as in previous learning outcome Methods of Assessment Written examinations; class tests; essay; experimental reports |
Understand the processes leading to drug discovery including biological target identification and chemical structure optimisation |
Teaching/Learning Methods and Strategies Lectures and workshops; guided independent study and literature review. This programme diverges substantially from the main BSc programme at Stage 3 with an emphasis on the application of underlying core chemical concepts and techniques in a medicinal chemistry context Methods of Assessment Written examinations; class tests; essay; experimental reports |
Be proficient in molecular modelling of biological systems and in silico skills for drug-discovery |
Teaching/Learning Methods and Strategies Lectures and computer workshops; guided independent study and literature review. Strategy as in previous learning outcome Methods of Assessment Written examinations; computer-based assignments; class tests; essay; |
MODULE INFORMATION
Stages and Modules
Module Title |
Module Code |
Level/ stage |
Credits |
Availability | Duration |
Pre-requisite |
Assessment | |||||
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S1 | S2 | Core | Option | Coursework % | Practical % | Examination % | ||||||
Introductory Mathematics for Chemists and Engineers | CHE1006 | 1 | 10 | YES | 12 weeks | N | YES | 100% | 0% | 0% | ||
Skills for Physical Chemistry | CHM1015 | 1 | 10 | YES | 12 weeks | N | YES | 100% | 0% | 0% | ||
Organic Chemistry Level 1 | CHM1101 | 1 | 30 | YES | YES | 24 weeks | N | YES | 15% | 15% | 70% | |
Inorganic Chemistry Level 1 | CHM1102 | 1 | 30 | YES | YES | 24 weeks | N | YES | 15% | 35% | 50% | |
Physical Theory | CCE1102 | 1 | 30 | YES | YES | 24 weeks | N | YES | 15% | 25% | 60% | |
Molecular Basis of Life for Medicinal Chemists | BIO1103 | 1 | 20 | YES | 12 weeks | N | YES | 70% | 30% | 0% | ||
Structural Chemistry | CHM2002 | 2 | 20 | YES | 24 weeks | N | YES | 100% | 0% | 0% | ||
Organic Chemistry 2 | CHM2003 | 2 | 20 | YES | 24 weeks | N | YES | 10% | 30% | 60% | ||
Inorganic Chemistry 2 | CHM2004 | 2 | 20 | YES | 24 weeks | N | YES | 5% | 25% | 70% | ||
Industrial and Green Chemistry | CHM2006 | 2 | 20 | YES | 24 weeks | N | YES | 100% | 0% | 0% | ||
Introductory Principles in Medicinal Chemistry | CHM2007 | 2 | 20 | YES | 12 weeks | N | YES | 35% | 15% | 50% | ||
Experimental Biochemistry | BIO2102 | 2 | 20 | YES | 12 weeks | N | YES | 60% | 0% | 40% | ||
Inorganic Chemistry 3 | CHM3001 | 3 | 20 | YES | YES | 24 weeks | N | YES | 15% | 0% | 85% | |
Advanced Chemistry Options | CHM3005 | 3 | 20 | YES | 24 weeks | N | YES | 0% | 0% | 100% | ||
Drug Development | CHM3016 | 3 | 20 | YES | 24 weeks | N | YES | 30% | 0% | 70% | ||
Organic Chemistry 3: Structure and Reactivity | CHM3002 | 3 | 20 | YES | YES | 24 weeks | N | YES | 0% | 0% | 100% | |
Advanced Practical Work in Medicinal Chemistry | CHM3012 | 3 | 40 | YES | YES | 24 weeks | N | YES | 100% | 0% | 0% | |
Advanced Organic Synthesis | CHM4002 | 4 | 20 | YES | 24 weeks | N | YES | 10% | 0% | 90% | ||
Advanced Inorganic Chemistry | CHM4005 | 4 | 20 | YES | YES | 24 weeks | N | YES | 10% | 0% | 90% | |
Chemical Research Project | CHM4001 | 4 | 60 | YES | YES | 24 weeks | N | YES | 100% | 0% | 0% | |
Options in Applied, Technical and Macromolecular Chemistry | CHM4006 | 4 | 20 | YES | 24 weeks | N | YES | 10% | 0% | 90% | ||
Frontiers in Drug Development (Medicinal Chemistry 4) | CHM4007 | 4 | 20 | YES | YES | 24 weeks | N | YES | 10% | 0% | 90% |
Notes
CHE1006 pre-req A-Level Maths