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Development of rapid diagnostic tools for plant toxins analysis

School of Biological Sciences | PHD

Applications are now CLOSED
Funding
Funded
Reference Number
SBIO-DFE-2025
Application Deadline
7 February 2025
Start Date
1 October 2025

Overview

The overall aim of the project is the design, construction and implementation of a rapid bionanosensor for the single and multiplex analysis of plant toxins. There are three key phases in this research project: Design phase, Construction Phase and Implementation of the rapid biosensor for determining plant toxins in environmental samples and food products.

Due to recent outbreaks of illness and death in Uganda in 2019 and previously in Afghanistan plant toxins are now an increasingly major concern for the food industry with new governing legislation and whereby improved point of site methods of analysis are increasing sought to prevent illness and death. To date no point of site testing device is readily available for these toxins for use in the field.

The overall aim of the project is the design, construction and implementation of both a single channel and multi-channel microfluidic nanosensor for the analysis of plant toxins in the field.

There are three key phases in this research project:
Design phase of the bionanosensor, Construction Phase and Implementation of the bionanosensor for determining plant toxins in food products.

The design phase of the sensor will include selection of target toxins of key importance such as tropane and pyrrolizidines alkaloids. The construction phase will investigate the most suitable design and portable detection system including smartphones for the lab-on-a-chip device. The implementation phase will be the validation of the device for determining plant toxins in cereal and honey samples both as lab-based tools and as a field based approach.

Candidate information: Minimum of an Upper Second Class Honours degree in Biochemistry, Molecular biology, Biotechnology from a UK or ROI HE provider, or an equivalent subject qualification acceptable to the University. Interest in natural toxins and rapid methods of analysis.

Funding Information

QUB School of Biological Sciences is advertising a range of projects for a limited number of DfE studentship awards. Shortlisted candidates across the range of projects will be interviewed in competition for a studentship. International candidates are welcome to apply but should note that only a very small number of the awards are available to International applicants; please refer to pages 4-7 of the DfE terms and conditions: https://www.economy-ni.gov.uk/publications/student-finance-postgraduate-studentships-terms-and-conditions

Project Summary
Supervisor

Professor Katrina Campbell

More Information

askmhls@qub.ac.uk

Research Profile


Mode of Study

Full-time: 3 years


Funding Body
DfE
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