Principal Investigator: Dr Ruth Hogg

Name of the Study: iSCREEN

Why is this Study important?

The economic and social impact of the I-SCREEN project extends beyond eye health. By enabling opticians and optometrists to contribute to primary care through AI-based disease detection, the project supports a shift in care-sharing.

Introducing AI-based decision support systems, the project brings precision medicine to ocular and systemic disease management. This system significantly reduces the disease burden, enabling early asymptomatic disease diagnosis with optimal cure perspectives.

What is the Research question/aim?:

The aim of the study is to predict conversion of early and intermediate AMD with functional vision to advanced AMD with irreversible loss of vision on an individual-based level over 2 years. The specific aims of this study are:

Identify and quantify focal and global alterations in the retina in regard to disease progression.

Assess the individual risk of disease progression in intermediate AMD patients converting to advanced AMD based on imaging.

Specify the course of disease in regard to the sequence of events that lead to the conversion to advanced AMD

Enhancing the ability to classify AMD using artificial intelligence in addition to traditional models.

What the Study involves:

Five visits of approximately 2 hours over a 2 year period, once every 6 months. This is a non interventional study where we assess Visual Function and under take retinal imaging

Who can take part in the Study?

Patients with early/intermediate AMD and early geographic atrophy

Contact Information:

Lucia Dalton    nicrfoptoms@qub.ac.uk                      

NI Clinical Research Facility,
U Floor, Belfast City Hospital,
Lisburn Road,

Belfast BT9 7AB