Hannah Maguire - Student Profile
Current Research Project: High-precision dosimetry for ultra-short, high dose-rate irradiation sources.
Laser-driven, ultra-short, electron beams can access unprecedented regimes of cell response to radiation, with potential to provide significant benefit to patients undergoing radiotherapy treatments. To precisely establish the effects of ultra-short irradiation on cells, it is mandatory to have accurate measurements of the dose delivered to both in-vitro and in-vivo samples. While dosimetric techniques are well established for relatively long irradiation times, detailed work must be done to establish techniques for dosimetry at ultra-short timescales.
My PhD research, under co-supervision with the National Physical Laboratory, will develop and test new methods for high-precision dosimetry using this novel regime of irradiating biological samples. I will gain expertise in a wide range of physical and engineering techniques, such as generating laser-driven radiation sources and characterising them, with the end goal of establishing a new scheme for radiotherapeutic cancer treatment.
Biography:
In July 2023, I graduated from Queen’s University Belfast with a Master’s degree in Physics with Medical Applications achieving a First Class Honours classification. I was awarded the O’Sullivan Prize for attaining the highest grade in the Medical Applications pathway. I have always been interested in medical physics. In my final year, I completed my Master’s research project in the Northern Ireland Cancer Centre alongside medical physicists to develop new quality assurance procedures to verify dose delivery from advanced radiotherapy treatment plans. I thoroughly enjoyed my project and was able to produce work that had a clinical impact in the Cancer Centre. This PhD project proved to be a natural progression in my education as I want to continue research in the medical physics field.
Supervisors:
Professor Gianluca Sarri and Professor Giuseppe Schettino (NPL)