Prof Gilmore’s research team are focused on understanding the processes which govern bacterial biofilm formation and tolerance to antibiotics, and the discovery of novel antibiotics and disinfectant approaches. His recent work has included the application of cold plasmas for biofilm decontamination, discovery of novel antibiotics and biocatalytic enzymes from extremely halophilic microorganisms (using both culture-based and metagenomic approaches) and uncovering novel druggable targets in bacterial biofilm formation among the ESKAPE pathogens using molecular tools to identify and inhibit proteolytic enzymes involved in biofilm development, as adjuvants to conventional antimicrobial agents.