Dr. Branco’s lab focuses on the role of microvasculature in cancer dissemination (metastasis). Endothelial cells are metabolically and physiologically diverse and respond to stimuli in an organ-specific fashion. Some endothelial-specific responses have been shown to modify cancer progression and disease outcome. We aim to understand how microvascular rearrangements contribute to organ function, remodelling and pre-disposition for metastatic disease.

Our lab uses primary endothelial cells and in vivo models, and state-of-the-art equipment and technology to assess physiological, pathological and metabolic parameters.