The aim of my research is to apply high throughput molecular genetic approaches, specifically next generation sequencing (NGS), to better understand disease processes such as diabetes in the eye and vascular system. One focus is upon small microRNAs and their role in regulating gene expression, communication between cells and their potential as circulating biomarkers.

We are also using single cell RNA sequencing to perform a ‘molecular dissection’ of the retina and study how the many cell types respond to diabetes.